Bis[(2-diphenylphosphino)ethyl]ammonium chloride, min. 97%

Name: Bis[(2-diphenylphosphino)ethyl]ammonium chloride, min. 97%
Brand: Zhengzhou Whchem

CAS：66534-97-2 | Bis[(2-diphenylphosphino)ethyl]ammonium chloride, min. 97% | Whchem

CAS: 66534-97-2

Other Names

Bis[2-(diphenylphosphino)ethyl]aMMoniuM chloride, 97+%;Bis[(2-diphenylphosphino)ethyl]ammonium chloride, min. 97%;Bis((2-diphenylphosphino)ethyl)aMMoniuM chloride;Bis[2-(diphenylphosphino)ethyl]amine hydrochloride;Bis[2-(diphenylphosphino)ethyl]amine monohydrochloride;N,N-Bis[2-(diphenylphosphino)ethyl]amine hydrochloride;Bis[(2-diphenylphosphino)ethyl]ammonium chloride 95%;BIS[(2-DIPHENYLPHOSPHINO)ETHYL]AMMONIUMCHLORIDE,MIN.97%

Structure - Bis[(2-diphenylphosphino)ethyl]ammonium chloride, min. 97%

Molecular Formula

Purity

>98%

Molecular Weight

477.95 g/mol

EINECS

Structure Available Verified Product

English Name	Bis[(2-diphenylphosphino)ethyl]ammonium chloride, min. 97%
English Synonyms	Bis[2-(diphenylphosphino)ethyl]aMMoniuM chloride, 97+%;Bis[(2-diphenylphosphino)ethyl]ammonium chloride, min. 97%;Bis((2-diphenylphosphino)ethyl)aMMoniuM chloride;Bis[2-(diphenylphosphino)ethyl]amine hydrochloride;Bis[2-(diphenylphosphino)ethyl]amine monohydrochloride;N,N-Bis[2-(diphenylphosphino)ethyl]amine hydrochloride;Bis[(2-diphenylphosphino)ethyl]ammonium chloride 95%;BIS[(2-DIPHENYLPHOSPHINO)ETHYL]AMMONIUMCHLORIDE,MIN.97%
CAS Number	66534-97-2
Molecular Formula	C28H30ClNP2
Molecular Weight	477.95 g/mol
EINECS Number
Related Categories	Achiral Phosphine;Aryl Phosphine;Amines;Building Blocks;C17 to C40+;Catalysis and Inorganic Chemistry;Chemical Synthesis;New Products for Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks
Mol File	Download MOL File
Structure Image

Property	Value
Melting point	175-180℃
Storage condition	under inert gas (nitrogen or Argon) at 2-8°C
Form	Solid
Color	White
Water solubility	Insoluble in water
Sensitivity	Air Sensitive
InChI	InChI=1S/C28H29NP2.ClH/c1-5-13-25(14-6-1)30(26-15-7-2-8-16-26)23-21-29-22-24-31(27-17-9-3-10-18-27)28-19-11-4-12-20-28;/h1-20,29H,21-24H2;1H
InChIKey	AVDUVHMGGDOIQI-UHFFFAOYSA-N
SMILES	[Cl-].C(CP(c1ccccc1)c2ccccc2)[NH2+]CCP(c3ccccc3)c4ccccc4

Bis[(2-diphenylphosphino)ethyl]ammonium chloride, min. 97% (CAS 66534-97-2) is an organophosphorus compound and phosphine-based material used in cross-coupling catalysis, ligand synthesis, flame retardants and electronic chemicals.

Zhengzhou Whchem supplies Bis[(2-diphenylphosphino)ethyl]ammonium chloride, min. 97% with >98% purity, supporting both laboratory research and industrial production.

Category	Description (English Translation)
Uses & Synthesis Methods Bis[2-(diphenylphosphino)ethyl]ammonium Chloride	Uses & Synthesis Methods Uses: Bis[2-(diphenylphosphino)ethyl]ammonium chloride is a phosphine-containing ammonium salt compound. It is commonly used as a ligand in coordination chemistry and homogeneous catalysis, particularly in transition metal-catalyzed cross-coupling reactions such as Suzuki, Heck, and Sonogashira reactions. It also serves as an intermediate in the synthesis of various bioactive molecules and pharmaceutical compounds, as well as in the preparation of bidentate phosphine ligands for asymmetric catalysis. Synthesis Methods: The compound can be synthesized by reacting bis(2-chloroethyl)ammonium chloride with diphenylphosphine in the presence of a strong base. Typically, diphenylphosphine is deprotonated with a base such as n-butyllithium or sodium hydride in an inert solvent like tetrahydrofuran (THF) or diethyl ether, followed by the addition of bis(2-chloroethyl)ammonium chloride. The reaction mixture is stirred at room temperature or under mild heating, and the resulting product is isolated by filtration, washed with an appropriate solvent, and dried under reduced pressure to afford the desired product as a white solid. The compound is typically stored under an inert atmosphere (nitrogen or argon) at 2-8°C due to its air sensitivity.

Category

Description (English Translation)

Uses & Synthesis Methods

Bis[2-(diphenylphosphino)ethyl]ammonium Chloride

Uses & Synthesis Methods

Uses: Bis[2-(diphenylphosphino)ethyl]ammonium chloride is a phosphine-containing ammonium salt compound. It is commonly used as a ligand in coordination chemistry and homogeneous catalysis, particularly in transition metal-catalyzed cross-coupling reactions such as Suzuki, Heck, and Sonogashira reactions. It also serves as an intermediate in the synthesis of various bioactive molecules and pharmaceutical compounds, as well as in the preparation of bidentate phosphine ligands for asymmetric catalysis.

Synthesis Methods: The compound can be synthesized by reacting bis(2-chloroethyl)ammonium chloride with diphenylphosphine in the presence of a strong base. Typically, diphenylphosphine is deprotonated with a base such as n-butyllithium or sodium hydride in an inert solvent like tetrahydrofuran (THF) or diethyl ether, followed by the addition of bis(2-chloroethyl)ammonium chloride. The reaction mixture is stirred at room temperature or under mild heating, and the resulting product is isolated by filtration, washed with an appropriate solvent, and dried under reduced pressure to afford the desired product as a white solid. The compound is typically stored under an inert atmosphere (nitrogen or argon) at 2-8°C due to its air sensitivity.

Category	Value
Hazard Symbol	Xi
Hazard Codes (R Phrases)	36/37/38
Safety Codes (S Phrases)	26
UN Number	UN 3335
WGK Germany	3
HS Code (Customs)	2932190090
Storage Category	11 - Combustible solids
Hazard Classification	Eye Irritation Category 2, Dermal Irritation Category 2, Specific Target Organ Toxicity - Single Exposure Category 3

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Bis[(2-diphenylphosphino)ethyl]ammonium chloride, min. 97%

CAS：66534-97-2 | Bis[(2-diphenylphosphino)ethyl]ammonium chloride, min. 97% | Whchem

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Bis[(2-diphenylphosphino)ethyl]ammonium chloride, min. 97%

CAS：66534-97-2 | Bis[(2-diphenylphosphino)ethyl]ammonium chloride, min. 97% | Whchem

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