O-(DIPHENYLPHOSPHINO)BENZONITRILE

Name: O-(DIPHENYLPHOSPHINO)BENZONITRILE
Brand: Zhengzhou Whchem

CAS：34825-99-5 | O-(DIPHENYLPHOSPHINO)BENZONITRILE | Whchem

CAS: 34825-99-5

Other Names

O-(DIPHENYLPHOSPHINO)BENZONITRILE;(2-Cyanophenyl)diphenylphosphine, min. 98%;(2-Cyanophenyl)diphenylphosphine,Min.98%;(2-Cyanophenyl)diphenylphosphine;2-(Diphenylphosphino)benzonitrile;2-diphenylphosphanylbenzonitrile;Benzonitrile, 2-(diphenylphosphino)-;(2-Cyanophenyl)diphenylphosphine - [C88878]

Structure - O-(DIPHENYLPHOSPHINO)BENZONITRILE

Molecular Formula

Purity

>98%

Molecular Weight

287.29 g/mol

EINECS

609-030-4

Structure Available Verified Product

English Name	O-(DIPHENYLPHOSPHINO)BENZONITRILE
English Synonyms	O-(DIPHENYLPHOSPHINO)BENZONITRILE;(2-Cyanophenyl)diphenylphosphine, min. 98%;(2-Cyanophenyl)diphenylphosphine,Min.98%;(2-Cyanophenyl)diphenylphosphine;2-(Diphenylphosphino)benzonitrile;2-diphenylphosphanylbenzonitrile;Benzonitrile, 2-(diphenylphosphino)-;(2-Cyanophenyl)diphenylphosphine - [C88878]
CAS Number	34825-99-5
Molecular Formula	C19H14NP
Molecular Weight	287.29 g/mol
EINECS Number	609-030-4
Related Categories	Achiral Phosphine;Aryl Phosphine;organophosphine ligand
Mol File	Download MOL File
Structure Image

Property	Value
Melting point	148-150°C
Boiling point	427.7±28.0 °C (Predicted)
Storage condition	2-8°C, protect from light, stored under nitrogen
Form	Powder
Color	White to off-white

O-(DIPHENYLPHOSPHINO)BENZONITRILE (CAS 34825-99-5) is an organophosphorus compound and phosphine-based material used in cross-coupling catalysis, ligand synthesis, flame retardants and electronic chemicals.

Zhengzhou Whchem supplies O-(DIPHENYLPHOSPHINO)BENZONITRILE with >98% purity, supporting both laboratory research and industrial production.

Category	Description (English Translation)
Uses & Synthesis Methods (2-Cyanophenyl)diphenylphosphine	Uses & Synthesis Methods Uses: (2-Cyanophenyl)diphenylphosphine is an organophosphorus compound. It is commonly used as a ligand in transition metal catalysis, particularly in palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura, Heck, and Buchwald-Hartwig reactions. The cyano group provides additional coordination ability and electronic tunability. It also serves as an intermediate in the synthesis of various bioactive molecules and pharmaceutical compounds. Synthesis Methods: The compound can be synthesized via the reaction of diphenylphosphine with 2-bromobenzonitrile in the presence of a base and a palladium catalyst. Typically, a mixture of diphenylphosphine, 2-bromobenzonitrile, a palladium source (e.g., Pd(OAc)₂), a ligand (if needed), and a base (e.g., potassium carbonate or sodium tert-butoxide) in an inert solvent such as toluene or DMF is heated under an inert atmosphere. The product is isolated by extraction, purified by column chromatography or recrystallization, and stored under nitrogen at 2-8°C, protected from light.

Category

Description (English Translation)

Uses & Synthesis Methods

(2-Cyanophenyl)diphenylphosphine

Uses & Synthesis Methods

Uses: (2-Cyanophenyl)diphenylphosphine is an organophosphorus compound. It is commonly used as a ligand in transition metal catalysis, particularly in palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura, Heck, and Buchwald-Hartwig reactions. The cyano group provides additional coordination ability and electronic tunability. It also serves as an intermediate in the synthesis of various bioactive molecules and pharmaceutical compounds.

Synthesis Methods: The compound can be synthesized via the reaction of diphenylphosphine with 2-bromobenzonitrile in the presence of a base and a palladium catalyst. Typically, a mixture of diphenylphosphine, 2-bromobenzonitrile, a palladium source (e.g., Pd(OAc)₂), a ligand (if needed), and a base (e.g., potassium carbonate or sodium tert-butoxide) in an inert solvent such as toluene or DMF is heated under an inert atmosphere. The product is isolated by extraction, purified by column chromatography or recrystallization, and stored under nitrogen at 2-8°C, protected from light.

Category	Value
HS Code (Customs)	2931.39.0030

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O-(DIPHENYLPHOSPHINO)BENZONITRILE

CAS：34825-99-5 | O-(DIPHENYLPHOSPHINO)BENZONITRILE | Whchem

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