(4-iodophenyl)diphenyl-Phosphine

Name: (4-iodophenyl)diphenyl-Phosphine
Brand: Zhengzhou Whchem

CAS：440111-10-4 | (4-iodophenyl)diphenyl-Phosphine | Whchem

CAS: 440111-10-4

Other Names

(4-iodophenyl)diphenyl-Phosphine;Phosphine, (4-iodophenyl)diphenyl-;(4-Iodophenyl)diphenylphosphane;(4-Iodophenyl)diphenylphosphane - [K89864]

Structure - (4-iodophenyl)diphenyl-Phosphine

Molecular Formula

Purity

>98%

Molecular Weight

388.18 g/mol

EINECS

Structure Available Verified Product

English Name	(4-iodophenyl)diphenyl-Phosphine
English Synonyms	(4-iodophenyl)diphenyl-Phosphine;Phosphine, (4-iodophenyl)diphenyl-;(4-Iodophenyl)diphenylphosphane;(4-Iodophenyl)diphenylphosphane - [K89864]
CAS Number	440111-10-4
Molecular Formula	C18H14IP
Molecular Weight	388.18 g/mol
EINECS Number
Related Categories
Mol File	Download MOL File
Structure Image

Property	Value
Boiling point	412.6±28.0 °C (Predicted)
Storage condition	Keep in dark place, Inert atmosphere, Room temperature

(4-iodophenyl)diphenyl-Phosphine (CAS 440111-10-4) is an organophosphorus compound and phosphine-based material used in cross-coupling catalysis, ligand synthesis, flame retardants and electronic chemicals.

Zhengzhou Whchem supplies (4-iodophenyl)diphenyl-Phosphine with >98% purity, supporting both laboratory research and industrial production.

Category	Description (English Translation)
Uses & Synthesis Methods (4-Iodophenyl)diphenylphosphine	Uses & Synthesis Methods Uses: (4-Iodophenyl)diphenylphosphine is a versatile organophosphorus compound containing both a phosphine group and an iodine substituent. It is commonly used as a ligand precursor in transition metal catalysis and as a building block in organic synthesis. The iodine group allows for further functionalization via cross-coupling reactions such as Suzuki-Miyaura, Sonogashira, and Buchwald-Hartwig reactions. It also serves as an intermediate in the synthesis of various phosphine ligands, bioactive molecules, and functional materials. Synthesis Methods: This compound can be synthesized by the reaction of diphenylphosphine with 1-iodo-4-bromobenzene or via halogen exchange methods. A typical procedure involves the lithiation of 4-iodobromobenzene followed by reaction with chlorodiphenylphosphine. Alternatively, it can be prepared by the reaction of (4-bromophenyl)diphenylphosphine with iodine in the presence of a copper catalyst. The reaction is usually carried out in an inert atmosphere using a solvent such as tetrahydrofuran or diethyl ether at low temperatures. The product is purified by column chromatography or recrystallization and stored in a dark place under inert atmosphere at room temperature.

Category

Description (English Translation)

Uses & Synthesis Methods

(4-Iodophenyl)diphenylphosphine

Uses & Synthesis Methods

Uses: (4-Iodophenyl)diphenylphosphine is a versatile organophosphorus compound containing both a phosphine group and an iodine substituent. It is commonly used as a ligand precursor in transition metal catalysis and as a building block in organic synthesis. The iodine group allows for further functionalization via cross-coupling reactions such as Suzuki-Miyaura, Sonogashira, and Buchwald-Hartwig reactions. It also serves as an intermediate in the synthesis of various phosphine ligands, bioactive molecules, and functional materials.

Synthesis Methods: This compound can be synthesized by the reaction of diphenylphosphine with 1-iodo-4-bromobenzene or via halogen exchange methods. A typical procedure involves the lithiation of 4-iodobromobenzene followed by reaction with chlorodiphenylphosphine. Alternatively, it can be prepared by the reaction of (4-bromophenyl)diphenylphosphine with iodine in the presence of a copper catalyst. The reaction is usually carried out in an inert atmosphere using a solvent such as tetrahydrofuran or diethyl ether at low temperatures. The product is purified by column chromatography or recrystallization and stored in a dark place under inert atmosphere at room temperature.

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(4-iodophenyl)diphenyl-Phosphine

CAS：440111-10-4 | (4-iodophenyl)diphenyl-Phosphine | Whchem

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(4-iodophenyl)diphenyl-Phosphine

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