(2-METHYLBENZYL)PHOSPHONIC ACID DIETHYL ESTER

Name: (2-METHYLBENZYL)PHOSPHONIC ACID DIETHYL ESTER
Brand: Zhengzhou Whchem

CAS：62778-16-9 | (2-METHYLBENZYL)PHOSPHONIC ACID DIETHYL ESTER | Whchem

CAS: 62778-16-9

Other Names

[(2-methylphenyl)methyl]-phosphonicacidiethylester;DIETHYL (2-METHYLBENZYL)PHOSPHONATE;DIETHYL (O-METHYLBENZYL)PHOSPHONATE;2-(DIETHYLPHOSPHONOMETHYL)TOLUENE;(2-METHYLBENZYL)PHOSPHONIC ACID DIETHYL ESTER;Diethyl(2-methylbenzyl)phosphonate, 98 %;[(2-Methylphenyl)methyl]phosphonic acid diethyl ester;(2-Methylbenzyl)-phosphonic acid dimethyl ester

Structure - (2-METHYLBENZYL)PHOSPHONIC ACID DIETHYL ESTER

Molecular Formula

Purity

>98%

Molecular Weight

242.25 g/mol

EINECS

Structure Available Verified Product

English Name	(2-METHYLBENZYL)PHOSPHONIC ACID DIETHYL ESTER
English Synonyms	[(2-methylphenyl)methyl]-phosphonicacidiethylester;DIETHYL (2-METHYLBENZYL)PHOSPHONATE;DIETHYL (O-METHYLBENZYL)PHOSPHONATE;2-(DIETHYLPHOSPHONOMETHYL)TOLUENE;(2-METHYLBENZYL)PHOSPHONIC ACID DIETHYL ESTER;Diethyl(2-methylbenzyl)phosphonate, 98 %;[(2-Methylphenyl)methyl]phosphonic acid diethyl ester;(2-Methylbenzyl)-phosphonic acid dimethyl ester
CAS Number	62778-16-9
Molecular Formula	C12H19O3P
Molecular Weight	242.25 g/mol
EINECS Number
Related Categories
Mol File	Download MOL File
Structure Image

Property	Value
Boiling point	122°C at 0.01 mmHg
Density	1.09
Refractive index	1.4980-1.5020
Storage condition	Sealed in dry, Room Temperature
Form	Clear liquid
Color	Colorless to almost colorless

(2-METHYLBENZYL)PHOSPHONIC ACID DIETHYL ESTER (CAS 62778-16-9) is an organophosphorus compound and phosphine-based material used in cross-coupling catalysis, ligand synthesis, flame retardants and electronic chemicals.

Zhengzhou Whchem supplies (2-METHYLBENZYL)PHOSPHONIC ACID DIETHYL ESTER with >98% purity, supporting both laboratory research and industrial production.

Category	Description (English Translation)
Uses & Synthesis Methods Diethyl (2-methylbenzyl)phosphonate	Uses & Synthesis Methods Uses: Diethyl (2-methylbenzyl)phosphonate is a phosphonate ester compound. It is commonly used as a precursor in organic synthesis for the preparation of various phosphonic acid derivatives and as a building block in the synthesis of biologically active molecules, pharmaceuticals, and agrochemicals. It is also utilized in the Horner-Wadsworth-Emmons (HWE) reaction for the construction of carbon-carbon double bonds, particularly in the synthesis of alkenes and conjugated dienes. Additionally, it serves as a ligand or ligand precursor in coordination chemistry and catalysis. Synthesis Methods: The compound can be synthesized by the Arbuzov reaction of 2-methylbenzyl bromide (or chloride) with triethyl phosphite. Typically, 2-methylbenzyl bromide is dissolved in an inert solvent such as toluene or xylene, and triethyl phosphite is added. The reaction mixture is heated under reflux for several hours until the reaction is complete. The resulting product is isolated by removal of the solvent and purified by distillation or column chromatography to afford the desired phosphonate ester as a colorless to pale yellow liquid. The product should be stored in a sealed, dry container at room temperature.

Category

Description (English Translation)

Uses & Synthesis Methods

Diethyl (2-methylbenzyl)phosphonate

Uses & Synthesis Methods

Uses: Diethyl (2-methylbenzyl)phosphonate is a phosphonate ester compound. It is commonly used as a precursor in organic synthesis for the preparation of various phosphonic acid derivatives and as a building block in the synthesis of biologically active molecules, pharmaceuticals, and agrochemicals. It is also utilized in the Horner-Wadsworth-Emmons (HWE) reaction for the construction of carbon-carbon double bonds, particularly in the synthesis of alkenes and conjugated dienes. Additionally, it serves as a ligand or ligand precursor in coordination chemistry and catalysis.

Synthesis Methods: The compound can be synthesized by the Arbuzov reaction of 2-methylbenzyl bromide (or chloride) with triethyl phosphite. Typically, 2-methylbenzyl bromide is dissolved in an inert solvent such as toluene or xylene, and triethyl phosphite is added. The reaction mixture is heated under reflux for several hours until the reaction is complete. The resulting product is isolated by removal of the solvent and purified by distillation or column chromatography to afford the desired phosphonate ester as a colorless to pale yellow liquid. The product should be stored in a sealed, dry container at room temperature.

Category	Value
TSCA	TSCA listed
HS Code (Customs)	2920.90.2000

Request Quotation or Technical Data

Fill out the form to request pricing, technical data sheets, or samples. Our team will respond within 24 hours.

[email protected]

Phone

8618638188764

Address

Parkin Building, Cuizhu Street, High-tech Development Zone, Zhengzhou, China

WeChat

Scan to connect

Quick response guaranteed

PRODUCT_CATEGORIES

Chemical Intermediates

Pharmaceutical Intermediates

OLED Intermediates

Advanced Organophosphorus Materials

Custom Synthesis

All Products

(2-METHYLBENZYL)PHOSPHONIC ACID DIETHYL ESTER

CAS：62778-16-9 | (2-METHYLBENZYL)PHOSPHONIC ACID DIETHYL ESTER | Whchem

You May Also Be Interested In

PENTAMETHYLENEBIS(TRIPHENYLPHOSPHONIUM BROMIDE)

(2-hydroxyphenyl)diphenylphosphine

BIS(2-METHOXYPHENYL)PHENYLPHOSPHINE

Request Quotation or Technical Data

(2-METHYLBENZYL)PHOSPHONIC ACID DIETHYL ESTER

CAS：62778-16-9 | (2-METHYLBENZYL)PHOSPHONIC ACID DIETHYL ESTER | Whchem

You May Also Be Interested In

PENTAMETHYLENEBIS(TRIPHENYLPHOSPHONIUM BROMIDE)

(2-hydroxyphenyl)diphenylphosphine

BIS(2-METHOXYPHENYL)PHENYLPHOSPHINE

Request Quotation or Technical Data

Product Inquiry