Bis(4-carboxyphenyl)phenyl-phosphine oxide

Name: Bis(4-carboxyphenyl)phenyl-phosphine oxide
Brand: Zhengzhou Whchem

CAS：803-19-0 | Bis(4-carboxyphenyl)phenyl-phosphine oxide | Whchem

CAS: 803-19-0

Other Names

BIS(4-CARBOXYPHENYL)PHENYLPHOSPHINE OXIDE;4,4'-(Phenylphosphinylidene)dibenzoic acid;4,4'-(Phenyloxophosphoranylidene)bisbenzoic acid;Bis(4-carboxyphenyl) phenyl phosphine oxide(BCPPO);4,4'-Phenylphosphinylidenebis(benzoic acid);Phenylbis(4-carboxyphenyl)phosphine oxide;4-[(4-carboxyphenyl)-phenylphosphoryl]benzoic acid;4-[(4-carboxyphenyl)-phenyl-phosphoryl]benzoic acid

Structure - Bis(4-carboxyphenyl)phenyl-phosphine oxide

Molecular Formula

Purity

>98%

Molecular Weight

366.3 g/mol

EINECS

212-355-0

Structure Available Verified Product

English Name	Bis(4-carboxyphenyl)phenyl-phosphine oxide
English Synonyms	BIS(4-CARBOXYPHENYL)PHENYLPHOSPHINE OXIDE;4,4'-(Phenylphosphinylidene)dibenzoic acid;4,4'-(Phenyloxophosphoranylidene)bisbenzoic acid;Bis(4-carboxyphenyl) phenyl phosphine oxide(BCPPO);4,4'-Phenylphosphinylidenebis(benzoic acid);Phenylbis(4-carboxyphenyl)phosphine oxide;4-[(4-carboxyphenyl)-phenylphosphoryl]benzoic acid;4-[(4-carboxyphenyl)-phenyl-phosphoryl]benzoic acid
CAS Number	803-19-0
Molecular Formula	C20H15O5P
Molecular Weight	366.3 g/mol
EINECS Number	212-355-0
Related Categories
Mol File	Download MOL File
Structure Image

Property	Value
Melting point	340-342 °C
Boiling point	642.9±55.0 °C (Predicted)
Density	1.42±0.1 g/cm³ (Predicted)
Storage condition	Sealed in dry, Room Temperature
Acidity Coefficient (pKa)	3.27±0.10 (Predicted)
Water solubility	73.26 mg/L (23 ºC)

Bis(4-carboxyphenyl)phenyl-phosphine oxide (CAS 803-19-0) is an organophosphorus compound and phosphine-based material used in cross-coupling catalysis, ligand synthesis, flame retardants and electronic chemicals.

Zhengzhou Whchem supplies Bis(4-carboxyphenyl)phenyl-phosphine oxide with >98% purity, supporting both laboratory research and industrial production.

Category	Description (English Translation)
Uses & Synthesis Methods Bis(4-carboxyphenyl)phenylphosphine Oxide	Uses & Synthesis Methods Uses: Bis(4-carboxyphenyl)phenylphosphine oxide is a phosphine oxide compound containing two carboxyl groups. It is primarily used as a building block for the synthesis of metal-organic frameworks (MOFs), coordination polymers, and other functional materials. It also serves as an intermediate in the synthesis of various bioactive molecules and pharmaceutical compounds. Its carboxyl groups allow for further derivatization, making it valuable in organic synthesis and materials chemistry. Synthesis Methods: The compound can be synthesized by the oxidation of bis(4-carboxyphenyl)phenylphosphine using an oxidizing agent such as hydrogen peroxide (H₂O₂) or m-chloroperbenzoic acid (m-CPBA). Typically, the phosphine precursor is dissolved in an appropriate solvent (e.g., acetone or dichloromethane), and the oxidizing agent is added slowly at room temperature or with gentle heating. The reaction mixture is stirred for several hours, and the product is isolated by filtration, washed with cold solvent, and dried to yield the desired phosphine oxide as a white to off-white solid. The product is stored sealed in a dry environment at room temperature due to its hygroscopic nature.

Category

Description (English Translation)

Uses & Synthesis Methods

Bis(4-carboxyphenyl)phenylphosphine Oxide

Uses & Synthesis Methods

Uses: Bis(4-carboxyphenyl)phenylphosphine oxide is a phosphine oxide compound containing two carboxyl groups. It is primarily used as a building block for the synthesis of metal-organic frameworks (MOFs), coordination polymers, and other functional materials. It also serves as an intermediate in the synthesis of various bioactive molecules and pharmaceutical compounds. Its carboxyl groups allow for further derivatization, making it valuable in organic synthesis and materials chemistry.

Synthesis Methods: The compound can be synthesized by the oxidation of bis(4-carboxyphenyl)phenylphosphine using an oxidizing agent such as hydrogen peroxide (H₂O₂) or m-chloroperbenzoic acid (m-CPBA). Typically, the phosphine precursor is dissolved in an appropriate solvent (e.g., acetone or dichloromethane), and the oxidizing agent is added slowly at room temperature or with gentle heating. The reaction mixture is stirred for several hours, and the product is isolated by filtration, washed with cold solvent, and dried to yield the desired phosphine oxide as a white to off-white solid. The product is stored sealed in a dry environment at room temperature due to its hygroscopic nature.

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Bis(4-carboxyphenyl)phenyl-phosphine oxide

CAS：803-19-0 | Bis(4-carboxyphenyl)phenyl-phosphine oxide | Whchem

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