4-Methylcumarin

Name: 4-Methylcumarin
Brand: Zhengzhou Whchem

CAS：607-71-6 | 4-Methylcumarin | Whchem

CAS: 607-71-6

Other Names

4-methylcoumarin;4-methyl-2h-1-benzopyran-2-on;4-methyl-2h-1-benzopyran-2-one;4-Methyl-2-oxo-2H-benzopyran;4-Methylbenzopyrone;4-methyl-1-benzopyran-2-one;4-Methyl-chromen-2-one;4-methyl-coumari

Molecular Formula

Purity

>97%

Molecular Weight

160.17 g/mol

EINECS

210-141-1

Structure Available Verified Product

English Name	4-Methylcumarin
English Synonyms	4-methylcoumarin;4-methyl-2h-1-benzopyran-2-on;4-methyl-2h-1-benzopyran-2-one;4-Methyl-2-oxo-2H-benzopyran;4-Methylbenzopyrone;4-methyl-1-benzopyran-2-one;4-Methyl-chromen-2-one;4-methyl-coumari
CAS Number	607-71-6
Molecular Formula	C10H8O2
Molecular Weight	160.17 g/mol
EINECS Number	210-141-1
Related Categories
Mol File	Download MOL File
Structure Image

Property	Value
Melting point	79.0 to 83.0 °C
Boiling point	180°C / 15 mmHg (lit.)
Density	1.0538 (rough estimate)
Refractive index	1.4108 (estimate)
Storage condition	2-8°C
Solubility	Almost insoluble in water, slightly soluble in cold alcohol, soluble in hot alcohol and in most oils.
Form	Powder crystals
Color	White to orange to green
Odor	Dry, hay-like, weak and persistent coumarin-like odor
Maximum Wavelength (λmax)	270 nm (EtOH) (lit.)
LogP	2.420 (est)

4-Methylcumarin (CAS 607-71-6) is a high-purity fine chemical intermediate widely used in organic synthesis, pharmaceutical R&D, agrochemical manufacturing and specialty chemical applications.

As a professional supplier, Zhengzhou Whchem provides 4-Methylcumarin with >97% purity, COA, structure confirmation and flexible packaging, available from research quantities to commercial scale with global shipping.

Category	Description (English Translation)
Uses & Synthesis Methods Chemical Properties: White needle-like or prismatic crystals. Melting point: 83-84°C. Soluble in ethanol and benzene. Uses: Used as an organic synthesis intermediate and as a fragrance ingredient. Production Method: Prepared by the condensation reaction of phenol with ethyl acetoacetate. Phenol, ethyl acetoacetate, and freshly distilled nitrobenzene are stirred together and heated to 100°C. A solution of anhydrous aluminum chloride in nitrobenzene is added dropwise over 45 minutes. The temperature is raised to 130°C and maintained for 3 hours until hydrogen chloride gas evolution ceases. After cooling to room temperature, hydrochloric acid is added under stirring to decompose excess aluminum chloride. Steam distillation is then carried out to remove unreacted ethyl acetoacetate and nitrobenzene. The remaining residue is allowed to stand, and the aqueous layer is separated. The oil layer is filtered and distilled under reduced pressure; nitrobenzene is first distilled off, followed by collection of the fraction boiling at 180-195°C (2.0 kPa), which is 4-methylcoumarin.

Category

Description (English Translation)

Uses & Synthesis Methods

Chemical Properties: White needle-like or prismatic crystals. Melting point: 83-84°C. Soluble in ethanol and benzene.

Uses: Used as an organic synthesis intermediate and as a fragrance ingredient.

Production Method: Prepared by the condensation reaction of phenol with ethyl acetoacetate. Phenol, ethyl acetoacetate, and freshly distilled nitrobenzene are stirred together and heated to 100°C. A solution of anhydrous aluminum chloride in nitrobenzene is added dropwise over 45 minutes. The temperature is raised to 130°C and maintained for 3 hours until hydrogen chloride gas evolution ceases. After cooling to room temperature, hydrochloric acid is added under stirring to decompose excess aluminum chloride. Steam distillation is then carried out to remove unreacted ethyl acetoacetate and nitrobenzene. The remaining residue is allowed to stand, and the aqueous layer is separated. The oil layer is filtered and distilled under reduced pressure; nitrobenzene is first distilled off, followed by collection of the fraction boiling at 180-195°C (2.0 kPa), which is 4-methylcoumarin.

Category	Value
HS Code (Customs)	2932.20.0500

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4-Methylcumarin

CAS：607-71-6 | 4-Methylcumarin | Whchem

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