2-CHLORO-1,4-BENZOQUINONE

Name: 2-CHLORO-1,4-BENZOQUINONE
Brand: Zhengzhou Whchem

CAS：695-99-8 | 2-CHLORO-1,4-BENZOQUINONE | Whchem

CAS: 695-99-8

Other Names

2-CHLORO-1,4-BENZOQUINONE;benzoquinone,2-chloro-;Chloro-1,4-benzoquinone;Chloro-p-benzoquinone;Chloroquinone;Monochloro-p-benzoquinone;Monochloroquinone;p-Benzoquinone, 2-chloro-

Molecular Formula

Purity

>97%

Molecular Weight

142.54 g/mol

EINECS

Structure Available Verified Product

English Name	2-CHLORO-1,4-BENZOQUINONE
English Synonyms	2-CHLORO-1,4-BENZOQUINONE;benzoquinone,2-chloro-;Chloro-1,4-benzoquinone;Chloro-p-benzoquinone;Chloroquinone;Monochloro-p-benzoquinone;Monochloroquinone;p-Benzoquinone, 2-chloro-
CAS Number	695-99-8
Molecular Formula	C6H3ClO2
Molecular Weight	142.54 g/mol
EINECS Number
Related Categories
Mol File	Download MOL File
Structure Image

Property	Value
Melting point	52-57 °C
Boiling point	210℃
Density	1.40
Refractive index	1.4620 (estimate)
Flash point	83℃
Storage condition	Storage temp. 2-8°C
Form	Crystals
Color	Yellow to brown
InChI	InChI=1S/C6H3ClO2/c7-5-3-4(8)1-2-6(5)9/h1-3H
InChIKey	WOGWYSWDBYCVDY-UHFFFAOYSA-N
SMILES	ClC1=CC(=O)C=CC1=O
CAS Database Reference	695-99-8 (CAS DataBase Reference)

2-CHLORO-1,4-BENZOQUINONE (CAS 695-99-8) is a high-purity fine chemical intermediate widely used in organic synthesis, pharmaceutical R&D, agrochemical manufacturing and specialty chemical applications.

As a professional supplier, Zhengzhou Whchem provides 2-CHLORO-1,4-BENZOQUINONE with >97% purity, COA, structure confirmation and flexible packaging, available from research quantities to commercial scale with global shipping.

Category	Description (English Translation)
Uses & Synthesis Methods Production Method: Starting Materials: 609-66-5 (2-Chlorobenzamide) 695-99-8 (2-Chloro-1,4-benzoquinone) General Procedure: Diacetoxyiodobenzene (5 mmol, 1.61 g) and NaHSO₄·H₂O (1 mmol, 0.138 g) were stirred in aqueous acetonitrile (5 mL water and 5 mL acetonitrile) at room temperature for 10-15 minutes. 2-Chlorobenzamide (1 mmol) was added to this reaction mixture, and stirring was continued until the reaction was complete (monitored by TLC). After completion, the reaction mixture was quenched with ice water and extracted with chloroform (3 × 10 mL). The combined chloroform layers were washed with water (3 × 20 mL), dried over anhydrous Na₂SO₄, and concentrated on a rotary evaporator to obtain the crude product. The crude product was further purified by silica gel column chromatography using ethyl acetate:hexane (1:9, v/v) as eluent to afford pure 2-chloro-1,4-benzoquinone. References: [1] Organic Letters, 2010, vol. 12, # 20, p. 4644 - 4647 [2] Synthetic Communications, 2014, vol. 44, # 4, p. 468 - 473

Category

Description (English Translation)

Uses & Synthesis Methods

Production Method:

Starting Materials:
609-66-5 (2-Chlorobenzamide)
695-99-8 (2-Chloro-1,4-benzoquinone)

General Procedure: Diacetoxyiodobenzene (5 mmol, 1.61 g) and NaHSO₄·H₂O (1 mmol, 0.138 g) were stirred in aqueous acetonitrile (5 mL water and 5 mL acetonitrile) at room temperature for 10-15 minutes. 2-Chlorobenzamide (1 mmol) was added to this reaction mixture, and stirring was continued until the reaction was complete (monitored by TLC). After completion, the reaction mixture was quenched with ice water and extracted with chloroform (3 × 10 mL). The combined chloroform layers were washed with water (3 × 20 mL), dried over anhydrous Na₂SO₄, and concentrated on a rotary evaporator to obtain the crude product. The crude product was further purified by silica gel column chromatography using ethyl acetate:hexane (1:9, v/v) as eluent to afford pure 2-chloro-1,4-benzoquinone.

References:
[1] Organic Letters, 2010, vol. 12, # 20, p. 4644 - 4647
[2] Synthetic Communications, 2014, vol. 44, # 4, p. 468 - 473

Category	Value
Hazard Symbol	Xi, Xn, F
Hazard Codes (R Phrases)	36/37/38-15-10
Safety Codes (S Phrases)	26-37/39-43-36-7/8
WGK Germany	3
HS Code (Customs)	29147000
Storage Category	11 - Combustible solids
Hazard Classification	Eye Irritation Category 2, Dermal Irritation Category 2, Specific Target Organ Toxicity - Single Exposure Category 3

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2-CHLORO-1,4-BENZOQUINONE

CAS：695-99-8 | 2-CHLORO-1,4-BENZOQUINONE | Whchem

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