2-AMINO-4'-CHLOROACETOPHENONE HYDROCHLORIDE

Name: 2-AMINO-4'-CHLOROACETOPHENONE HYDROCHLORIDE
Brand: Zhengzhou Whchem

CAS：5467-71-0 | 2-AMINO-4'-CHLOROACETOPHENONE HYDROCHLORIDE | Whchem

CAS: 5467-71-0

Other Names

2-amino-4’-chloro-acetophenonhydrochloride;4-chloro-omega-aminoacetophenonehydrochloride;2-AMINO-1-(4-CHLOROPHENYL)-1-ETHANONE HYDROCHLORIDE;2-AMINO-1-(4-CHLORO-PHENYL)-ETHANONE HYDROCHLORIDE;2-Amino-1-(4-chlorophenyl)ethan-1-one hydrochloride;4-Chlorophenacylamine hydrochloride;2-Amino-4Chloroacetophenone Hcl;2-Amino-1-(4-chlorophenyl)ethan-1-one hydrochloride 95%

Structure - 2-AMINO-4'-CHLOROACETOPHENONE HYDROCHLORIDE

Molecular Formula

Purity

>98%

Molecular Weight

206.07 g/mol

EINECS

Structure Available Verified Product

English Name	2-AMINO-4'-CHLOROACETOPHENONE HYDROCHLORIDE
English Synonyms	2-amino-4’-chloro-acetophenonhydrochloride;4-chloro-omega-aminoacetophenonehydrochloride;2-AMINO-1-(4-CHLOROPHENYL)-1-ETHANONE HYDROCHLORIDE;2-AMINO-1-(4-CHLORO-PHENYL)-ETHANONE HYDROCHLORIDE;2-Amino-1-(4-chlorophenyl)ethan-1-one hydrochloride;4-Chlorophenacylamine hydrochloride;2-Amino-4Chloroacetophenone Hcl;2-Amino-1-(4-chlorophenyl)ethan-1-one hydrochloride 95%
CAS Number	5467-71-0
Molecular Formula	C8H9Cl2NO
Molecular Weight	206.07 g/mol
EINECS Number
Related Categories
Mol File	Download MOL File
Structure Image

Property	Value
Melting point	262 °C
Storage condition	-20°C, sealed storage, away from moisture
Appearance	White to pale yellow solid
InChI	InChI=1S/C8H8ClNO.ClH/c9-7-3-1-6(2-4-7)8(11)5-10;/h1-4H,5,10H2;1H
InChIKey	OVKMQHKVUWBLSV-UHFFFAOYSA-N
SMILES	C1(C(=O)CN)C=CC(Cl)=CC=1.Cl
CAS Database Reference	5467-71-0 (CAS DataBase Reference)

2-AMINO-4'-CHLOROACETOPHENONE HYDROCHLORIDE (CAS 5467-71-0) is a pharmaceutical intermediate widely used in drug discovery, API synthesis and commercial pharmaceutical manufacturing.

Zhengzhou Whchem supplies 2-AMINO-4'-CHLOROACETOPHENONE HYDROCHLORIDE with >98% purity, complete analytical documentation and reliable global logistics for R&D and production needs.

Category	Description (English Translation)
Uses & Synthesis Methods 2-Amino-4'-chloroacetophenone Hydrochloride	Uses & Synthesis Methods Uses: 2-Amino-4'-chloroacetophenone hydrochloride is an important organic synthesis intermediate. It is commonly used in the synthesis of various pharmaceutical compounds, particularly in the preparation of heterocyclic compounds such as thiazoles, imidazoles, and benzodiazepines. It also serves as a building block in the synthesis of bioactive molecules and potential drug candidates. Synthesis Methods: The compound can be synthesized by the chlorination of 4'-chloroacetophenone followed by amination. A typical method involves the bromination or chlorination of 4'-chloroacetophenone to yield the corresponding α-haloacetophenone derivative, which is then reacted with hexamethylenetetramine (the Delepine reaction) or with ammonia/amine to introduce the amino group. The resulting free base is then converted to its hydrochloride salt by treatment with hydrochloric acid. Purification is typically achieved by recrystallization from an appropriate solvent such as ethanol or methanol. td>

Category

Description (English Translation)

Uses & Synthesis Methods

2-Amino-4'-chloroacetophenone Hydrochloride

Uses & Synthesis Methods

Uses: 2-Amino-4'-chloroacetophenone hydrochloride is an important organic synthesis intermediate. It is commonly used in the synthesis of various pharmaceutical compounds, particularly in the preparation of heterocyclic compounds such as thiazoles, imidazoles, and benzodiazepines. It also serves as a building block in the synthesis of bioactive molecules and potential drug candidates.

Synthesis Methods: The compound can be synthesized by the chlorination of 4'-chloroacetophenone followed by amination. A typical method involves the bromination or chlorination of 4'-chloroacetophenone to yield the corresponding α-haloacetophenone derivative, which is then reacted with hexamethylenetetramine (the Delepine reaction) or with ammonia/amine to introduce the amino group. The resulting free base is then converted to its hydrochloride salt by treatment with hydrochloric acid. Purification is typically achieved by recrystallization from an appropriate solvent such as ethanol or methanol.
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Category	Value
Hazard Symbol	Xi
Hazard Class	IRRITANT
HS Code (Customs)	2922390090

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2-AMINO-4'-CHLOROACETOPHENONE HYDROCHLORIDE

CAS：5467-71-0 | 2-AMINO-4'-CHLOROACETOPHENONE HYDROCHLORIDE | Whchem

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